Glabridin（59870-68-7）

Brief Introduction Glycyrrhizin is a natural whitening agent separated from licorice flavonoids, which are extracted from the roots of certain varieties of licorice plants (such as Ural licorice, Glycyrrhiza biloba, Glycyrrhiza glabra, etc.), completely natural, pollution-free, and have no side effects on human body. It is a reddish brown powder at normal temperature, insoluble in water, and easily soluble in organic solvents, such as ethanol, propylene glycol, 1,3-butanediol, etc. Glycyrrhiza glabra is a perennial herb that grows in southern Europe, Asia and the Mediterranean, and is widely planted in Russia, Spain, Iran and India. Guanggan Chemicalbook can dissipate phlegm, moisturize skin, anti-inflammatory, anti-filtering pathogens, anti-hepatotoxin and antibacterial. Because of these curative effects of licorice, it has been widely studied in medicine and food. Glycyrrhiza uralensis can be used in cosmetics. It has whitening, anti-inflammatory, antibacterial and antioxidant effects. It is a very valuable cosmetic raw material. Light glycyrrhizin is known as "whitening gold" because of its efficient inhibition of reactive oxygen species and melanin. First, it is praised for its whitening effect. Second, the price of single gram of light glycyrrhizin is equivalent to gold. Only a few brands dare to use it as a whitening ingredient.

Efficacy and function: Light glycyrrhizin has a strong antibacterial effect, prevents inflammation, pigmentation and rough skin caused by ultraviolet rays, and can remove superoxide ions and inhibit hemolysis caused by hydrogen peroxide. It can inhibit the activity of tyrosinase, but also inhibit the activity of dopa pigmentation and DHICA oxidase. It is a fast, efficient and green whitening and freckle-removing cosmetic additive, It has the ability to scavenge oxygen free radicals similar to SOD (superoxide dismutase), and has the ability to resist oxygen free radicals similar to vitamin E. In addition, light glycyrrhizin also has strong oxidation effect, anti-atherosclerosis effect and Chemicalbook effect on lowering blood lipid and blood pressure.

Pharmacological action Guangliquiridine is one of the main flavonoids in Glycyrrhiza glabra. It shows a strong anti-free radical oxidation effect in the cytochrome P450/NADPH oxidation system, and can significantly inhibit the free radicals produced in the metabolism process of the body, so as to avoid being damaged by free radical oxidation of biological macromolecules (low density lipoprotein LDL, DNA) and cell walls sensitive to oxidation. It can prevent and cure some pathological changes related to free radical oxidation, such as atherosclerosis, cell aging, etc. In addition, glycyrrhizin also has the effect of lowering blood lipid and blood pressure.

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