Onjisaponin D(66663-91-0)

Basic physical and chemical properties: chemical formula: C57H92O27

CAS No.: 66663-91-0

Melting point: 221-226

Specific rotation: - 41.5 (c, 1 in MeOHChemicalbook)

Molecular weight: 1209.32000

Appearance: white needle crystal

Purity: ≥ 98%

Solubility: soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

Biological activity: PolygalacinD (PGD) is a biologically active compound with anticancer and anti-proliferative properties isolated from Platycodon grandiflorum. PolygalacinD inhibits the expression of IAP protein family, including survival Chemicalbook protein, cIAP-1 and cIAP-2 protein, and by inhibiting GSK3 β， The phosphorylation of Akt and the expression of PI3K block the PI3K/Akt pathway. PolygalacinD induces apoptosis through PI3K/Akt pathway.

Purpose: To promote intelligence, reduce myocardial damage, relieve cough and expectorant effect.

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