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  • Ginkgolide B(15291-77-7)
Ginkgolide B(15291-77-7)

Ginkgolide B(15291-77-7)

Chemical Properties: Derived from Ginkgobiloba Leaf P.E of Ginkgo biloba Leaf Extract
Uses: Used for content determination/identification/pharmacological experiments, etc.
Pharmacological effects: Ginkgolide B has the strongest physiological activity among ginkgolides, and is the strongest platelet activating factor antagonist found in Chemicalbook so far, and can be used clinically to treat thrombosis, acute pancreatitis and cardiovascular diseases , can also be used for the treatment of metastatic cancer, and it also has protective effect on damaged neurons, and has anti-oxidation and anti-aging effects.

  • Ginkgolide B is a diterpene lactone compound extracted from the root and dry leaves of the Ginkgo biloba plant of the family Ginkgo biloba. It is easily soluble in solvents such as ethyl acetate, methanol, ethanol, and dimethyl sulfoxide. The molecule contains Multiple reducing hydroxyl functional groups can directly scavenge and capture free radicals, inhibit the formation of harmful substances such as MDA, and have obvious anti-lipid peroxidation damage, thus delaying aging. At the same time, it has a specific antagonistic effect on platelet activating factor (PAF). Ginkgo biloba leaves and root bark contain a series of bitter diterpene lactone compounds: Ginkgolide A (GinkgolideA), Ginkgolide B (GinkgolideB), Ginkgolide C (GinkgolideC) and Ginkgolide M; Ester B has the strongest physiological activity, and is the strongest antagonist of platelet activity Chemicalbooking factor found so far. It can be used clinically for the treatment of thrombosis, acute pancreatitis and cardiovascular diseases, and can also be used for the treatment of metastatic cancer. It also has a protective effect on damaged neurons, and has anti-oxidation and anti-aging effects. Ginkgolide b injection has a single and clear composition, significant curative effect, good safety, and high market acceptance. It is a rare new intravenous injection form of traditional Chinese medicine in recent years. The function of ginkgolide b injection mainly treats phlegm and blood stasis dispelling, dredging the meridians and relaxing the collaterals. For the treatment of ischemic stroke syndrome of obstruction of collaterals by phlegm and blood stasis. Ginkgolide A has a significant preventive effect on stress ulcers, has a recovery effect on cholinergic damage to memory function, can prevent the reduction of ChAT activity, relieve and improve myocardial ischemia, can inhibit the occurrence of DAD, and has anti-anxiety effects effect. The above information was edited by Andy of Chemicalbook


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