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  • Schisantherin A(58546-56-8)
Schisantherin A(58546-56-8)

Schisantherin A(58546-56-8)

Chemical properties Rectangular crystal (ethanol), mp122 ℃~124 ℃[ α] D23-175 ° (c=0.12, chloroform). Easily soluble in benzene, chloroform and acetone, soluble in methanol and ethanol, insoluble in petroleum ether and insoluble in water. Seven biphenyl cyclooctene lignans with transaminase activity were isolated from the ethanol extract of Schisandra chinensis nuts, including deoxyschizandrin, Schisandra chinensis, Schisandra chinensis B, Schisandra chinensis C, Schisandra chinensis Chemicalbook alcohol B, Schisandra chinensis ester A and Schisandra chinensis ester B. All seven ingredients have the effect of reducing SGPT, promoting the generation of hepatic glycogen and prolonging the sleep time of pentobarbital. Schisandrin B has the strongest effect on reducing SGPT, Schisandrin B has the most significant effect on promoting the generation of hepatic glycogen, and Schisandrin C has the most prominent effect on prolonging the sleep time of pentobarbital.

Biological activity: Schisantherin A (Gomisin C, Schisanwilsonin H, Arisanschinin K) is a kind of schisandrin, which has the activities of stopping the chemicalbook cough, sedation, anti-inflammatory, anti-osteoporosis, neuroprotection, cognitive enhancement and cardiac protection. SchisanterinA can also pass the I κ B α Degradation inhibition p65-NF- κ B shifts to the nucleus.

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