Andrographolide(5508-58-7)

Plant extract: Andrographolide is a diterpenoid lactone compound extracted from Andrographis paniculata, which is one of the main effective ingredients of the traditional Chinese medicine Andrographis paniculata. Its appearance is white square prism or flaky crystal, odorless and bitter. Andrographolide is soluble in boiling ethanol k, slightly soluble in methanol or ethanol, very slightly soluble in chloroform, and almost insoluble in water or ether. It has the effect of dispelling heat and detoxicating, diminishing inflammation and relieving pain, and has special curative effect on bacterial and viral upper respiratory tract infections and dysentery. It is known as natural antibiotic drugs.

Application: The main effective component of Andrographis paniculata is diterpenoid lactone, which has anti-inflammatory, antibacterial, anti-viral and other effects. Among them, andrographolide and dehydroandrographolide have the highest content, and dehydroandrographolide is the most potent of andrographolide compounds. Drugs made from andrographolide or dehydrated andrographolide and its derivatives, such as andrographolide tablets, andrographolide injection, and andrographolide injection, have been widely used in clinical practice.

Chemical property: white square or rectangular crystal. Melting point 224-230 ℃ (decomposition). Soluble in boiling ethanol, slightly soluble in methanol or ethanol, slightly soluble in chloroform, insoluble in water or ether. It is odorless and tastes bitter.

Uses: Antibacterial, anti-inflammatory, antipyretic, antidote. It is applicable to the treatment of bacterial dysentery, acute gastroenteritis, epidemic mumps, tonsillitis, pharyngitis, upper respiratory tract infection, etc

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