Cytisine(485-35-8)

Overview: genistein- α］［ 1, 5] diazaroxin-8-one, molecular formula: C11H14N2O, molecular weight: (190.24), also known as genistein, indicine, and cynancine, belongs to quinorizidine alkaloids, is a derivative of pyridine, and is one of the main alkaloids in Sophora alopecuroides, which is mostly distributed in leguminous and berberiferous plants, and has many pharmacological effects such as anti-arrhythmia, anti-microbial infection, anti-ulcer, and raising white blood cells, Clinically, it is mainly used for rescuing surgical trauma, war injury, asphyxiant poison, cyanide poison, anesthetic and other symptoms such as reflex apnea caused by poisoning, respiratory and cardiovascular failure caused by infectious diseases, shock, collapse and neonatal asphyxia.

Function: genistein is an antiarrhythmic drug. It can reduce myocardial stress and conductivity, slow heart rate and inhibit myocardial contractility. Clinically, it is used to treat tachycardia. This product can reduce the stress, conductivity and contractility of myocardium, slow down the heart rate and prolong the refractory period. It is mainly used for ventricular tachycardia and functional palpitation. It has contractive effect on the uterus, and can also be used to induce labor and uterine bleeding. It is also used to prepare hibernation mixture for artificial hibernation therapy.

The effect of genistein on the respiratory system is similar to that of nicotine, which can excite the breath reflexively, and its excitatory effect is stronger than that of the same dose of kaemporine. In clinical use, 0.15% aqueous solution is injected intramuscularly or intravenously to rescue surgical trauma, asphyxiant agents, cyanogens, anesthetics and other toxic reflex apnea, or infectious diseases cause respiratory and cardiovascular failure and shock Collapse state and neonatal asphyxia, etc. In recent years, genistein, as an effective drug for smoking cessation, has attracted the attention of the international medical community.

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