Biological activity: LicochalconeD (LicoD, LCD, LD) is a kind of flavonoids isolated from the Chinese herbal medicine Glycyrrhiza inflata, which has the characteristics of antioxidation, anti-inflammatory and anticancer. LicochalconeD can inhibit NF in LPS signal pathway- κ Phosphorylation Chemicalbook of Bp65. LicochalconeD can inhibit the activities of JAK2, EGFR and Met (c-Met) and induce ROS-dependent apoptosis. LicochalconeD can also induce the activation of caspases and the cleavage of poly (ADP-ribose) polymerase (PARP).
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Glycyrrhiza uralensis Fisch.
For content determination/identification/pharmacological experiments, etc.
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