Troxerutin（7085-55-4）

Production method: Troxerutin can be made into suitable soft material with starch as filler and 95% ethanol as wetting agent, then granulated and dried, and then granulated with nylon sieve bottom, and mixed evenly with magnesium stearate and talcum powder as lubricant, and then compressed. Its appearance is smooth and smooth, the tablet hardness is good, the tablet weight difference is stable, and the content is qualified. Through this process, the fluidity and outflow velocity of troxerutin powder can be improved, so that the outflow velocity of particles is fast and uniform, so as to ensure the stability of sheet difference. At the same time, the amount of fine powder can be reduced through granulation, the chance of contact between powder and punch can be reduced, and the phenomenon of drawing die can be avoided. This process needs no drying, consumes less energy and has low cost, and is suitable for industrial production. Chemicalbook analgesic mechanism Troxerutin is a water-soluble derivative of rutin and has quercetin similar to rutin, while quercetin and other glycosides with quercetin mother nucleus (such as rutin, hypericin, etc.) have significant central and peripheral analgesic effects, and its analgesic mechanism is related to reducing the content of calcium ions in nerve tissue. Therefore, we speculate that the analgesic mechanism of troxerutin may also be related to calcium antagonism. Troxerutin is a water-soluble derivative of rutin, which has similar pharmacological effects with rutin and has higher biological availability, but it is more difficult to enter the central nervous system than rutin. This may be the reason for the specificity of the analgesic effect of troxerutin.