Yohimbine hydrochloride（65-19-0）

Overview: Yohimbine hydrochloride (molecular structure formula C21H26N2O3HCL, English Yohimbine hydrochloride), also known as Weibizhi, Yohimbine hydrochloride, Yohimbine hydrochloride, Comfort Lotte Tablets, Comfort Lotte, is white to creamy white fine powder, slightly fragrant, bitter and astringent, melting point 288 ℃~290 ℃, easily soluble in chloroform, methanol, ethanol, and slightly soluble in water. The plant is derived from the dry bark of the wild African plant Corynante Yohimbe or the extract of the bark of the West African plant Conan of Rubiaceae. Its pharmacological effect is to increase sexual muscle tone and inhibit urine without damage; Accelerate body energy metabolism and increase energy supply. Clinical single dose is used to treat male impotence and sexual dysfunction. The mechanism of action is to selectively block presynaptic α 2 receptors, promote the release of norepinephrine, release more norepinephrine from the nerve endings of the cavernous body, reduce the return of the penis vein, facilitate hyperemia and erection, and increase the secretion of sexual fluid. When used in small amount, it can make the perineum swell, stimulate the erectile center of the spinal cord and make the sexual function hyperfunction.