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Corosolic acid(4547-24-4)

Physical and chemical properties Corosolic acid is white amorphous powder (methanol), also known as plant insulin, 2 α- Hydroxy ursolic acid, which is Barabba extract and Lagerstroemia speciosa extract, belongs to α- Aromatic resin alcohol-type or Usane pentacyclic triterpenoid compounds, soluble in petroleum ether, benzene, chloroform, pyrrolidine and other organic solvents, insoluble in water, soluble in hot ethanol and methanol. Under anhydrous conditions, it will react with strong acid (sulfuric acid, phosphoric acid, perchloric acid), moderately strong acid (trichloroacetic acid) or Lewis acid (zinc chloride, aluminum trichloride, antimony trichloride), and color reaction or fluorescence will occur.

Clinical application and efficacy department: As a new plant medicine for preventing obesity and type II diabetes and a functional natural health food pharmaceutical raw material, rosolic acid has become a popular product in the market. At present, the natural product has been marketed as a nutritional supplement in the United States, and the phase III clinical trial for the treatment of diabetes has been carried out at the same time. It will pass the FDA certification in the near future. Compared with insulin injection, it has obvious oral effect, less toxic and side effects, convenient use and other advantages in the treatment of diabetes, and its effect is equivalent to that of insulin injection. The content of Corosolic acid in plants is generally very low. Even in the concentrated extract of Lagerstroemia speciosa with high content of Corosolic acid, the content of Corosolic acid is only about 0.01%; In the chemicalbook alcohol concentrated extract of Barnaba leaves, the content of Corosolic acid is only about 1%. After years of research, Microherb has successfully separated 98% high-purity corosonic acid by using advanced chromatographic separation technology, which is used for experimental and clinical studies on the efficacy and toxicology of the prevention and treatment of obesity and type II diabetes. The main effects of Corosolic acid are as follows:


1. It can regulate the content of insulin and blood sugar in the body, and has an obvious tendency to lose weight. The process is relatively slow and does not require dieting. So it can be used to lose weight.


2. This product has significant hypoglycemic effect.


3. It has significant inhibitory effect on inflammatory reaction, and its anti-inflammatory effect is stronger than that of commercially available anti-inflammatory drugs such as indomethacin.


4. It can inhibit the growth of a variety of tumor cells and has broad prospects in this field.


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