Dauricine（524-17-4）

Pharmacological activity: The pharmacological action of dauricine is similar to that of quinidine. It can reduce myocardial contractility, inhibit self-discipline, prolong functional refractory period, reduce excitability, reduce right heart frequency, reduce the amplitude and rate of the rise of action potential zero-phase chemicalbook, extend the duration of action potential, and shorten the duration of atrial action potential with anticholine acetate. This product has no selective effect on the transmembrane ion transport of myocardial cells, but has dual effects of resisting calcium and sodium.

Chemical properties: the rhizome from the plant of Tetrandraceae, Pueraria dauricus (Dioscorea), is used for content determination/identification/pharmacological experiment, etc.

Pharmacological effect: reduce self-discipline and myocardial excitability, slow heart rate and inhibit myocardial contractility. It has the characteristics of fast onset and slow recovery. Absorbed by the gastrointestinal tract, 1Chemicalbook-2h reached the peak of blood drug concentration, and excreted through stool and urine. This product is a broad-spectrum antiarrhythmic drug, suitable for tachyarrhythmia, especially for atrial, junctional and ventricular premature beats; It is also effective for preexcitation syndrome with ventricular tachycardia; But the effect on atrial flutter and atrial fibrillation is poor.

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